False pepperwort leaves found to be effective against urolithiasis (kidney stones)

False pepperwort (Marsilea crenata), also known as water clover, has been used to treat kidney disturbances in various cultures. A study published in the American Journal of Animal and Veterinary Sciences investigates if the herb’s medicinal benefits also extend to dogs.

• The researcher aimed to determine the potential of false pepperwort leaf and stalk extract as a treatment for urolithiasis or kidney stones in animals.
• An animal model was created composed of Wistar rats. The animals were divided into six groups: negative control, positive control (treated with 0.75 percent ethylene glycol (EG) and two percent ammonium chloride (AC)); and four groups of preventive control (given 5, 10, 20, and 40 percent M. crenata leaves and stalks juices). The treatment lasted for 10 days.
• The researcher took note of several indicators: Blood Urea Nitrogen (BUN) and serum creatinine, urine creatinine, and creatinine clearance (C_cr).
• After the treatment, the author noted reductions in both BUN and C_cr.

The results were interpreted as proof that false pepperwort extracts can help treat kidney issues characteristic of urolithiasis.

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Journal Reference:

Murwani S. PREVENTIVE EFFECT OF MARSILEACRENATA LEAVES AND STALKS JUICES AGAINST UROLITHIASIS SHOWED BY IMPROVING OF KIDNEY FUNCTION. American Journal of Animal and Veterinary Sciences. 2016;11(1):47–54. DOI: 10.3844/ajavsp.2016.47.54