Ease inflammation with dwarf lilyturf


A study published in BMC Complementary and Alternative Medicine reported that Ophiopogon japonicas (dwarf lilyturf) can be potentially used to create therapeutic medicine for inflammatory health conditions. According to the authors, the plant, which has been used in traditional Chinese medicine to cure inflammation and chronic diseases, can be examined to determine if it has anti-inflammatory properties.

  • For thousands of years, O. japonicas has been used as a traditional Chinese medicine to treat acute and chronic inflammation. In the past, the plant was also used to address cardiovascular diseases such as thrombotic diseases.
  • Earlier phytochemical studies determined that O. japonicus has compounds with anti-inflammatory properties.
  • The goal of the researchers involved in the study was to analyze and isolate the anti-inflammatory compounds from the rhizome of O. japonicas.
  • For the study, the researchers isolated the compounds in the plant using various column chromatography. The structures of the compounds were then were identified via nuclear magnetic resonance spectrum (NMR) and mass spectrum (MS).
  • The anti-inflammatory effects of thirteen compounds in LPS-induced RAW 264.7 macrophage cells were measured through the following methods: cell viability assay, nitric oxide assay, enzyme-linked immunosorbent assay, quantitative real-time PCR analysis and western blotting analysis.
  • The study findings revealed the existence of one new and twelve known compounds, which were made up of mostly homoisoflavonoids, from O. japonicas. The new compound was identified as 4?-O-Demethylophiopogonanone E.

The results of the study showed that the new compound, 4?-O-Demethylophiopogonanone E, has potential as a promising ingredient source of therapeutic medicine for inflammatory diseases.

Find the full text of study at this link.

You can read more articles about the possible health benefits of the dwarf lilyturf at Herbs.news.

Journal Reference: 

Zhao JW, Chen DS, Deng CS, Wang Q, Zhu W, Lin L. EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF COMPOUNDS ISOLATED FROM THE RHIZOME OF OPHIOPOGON JAPONICAS. BMC Complementary and Alternative Medicine. 2017;17(1). DOI: 10.1186/s12906-016-1539-5



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