10/02/2018 / By Ellaine Castillo
The potent carcinogen 4-nitroquinoline 1-oxide (4-NQO) causes cancer by inducing oxidative stress. Researchers from Vellore Institute of Technology found that the Indian trumpet flower (Oroxylum indicum (L.)) inhibits oxidative stress and protects the liver from damage that could progress to cancer. Their finding, which was published in BMC Complementary and Alternative Medicine, was based on the results of in vivo experiments.
The results of this study show that leaf extracts of the Indian trumpet flower works in a dose-dependent manner to reduce 4-NQO induced oxidative stress, as well as protect the liver from oxidative stress-induced tissue damage. These prove that the Indian trumpet flower anti-hepatotoxic, antioxidant and hepatoprotective activity, which they hypothesized to be caused by bioactive compounds in the extract, specifically, baicalein.
Read the full text of the study at this link.
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Journal Reference:
Mohan S, Thiagarajan K, Sundaramoorthy B, Gurung V, Barpande M, Agarwal S, Chandrasekaran R. ALLEVIATION OF 4-NITROQUINOLINE 1-OXIDE INDUCED OXIDATIVE STRESS BY OROXYLUM INDICUM (L.) LEAF EXTRACT IN ALBINO WISTAR RATS. BMC Complementary and Alternative Medicine. 19 July 2016;16(229). DOI: 10.1186/s12906-016-1186-x
Tagged Under: 4-nitroquinoline 1-oxide, 4-NQO, alternative cures, alternative medicine, anti-hepatotoxic, antioxidant, baicalein, cancer, cancer treatment, carcinogen, chrysin, Hepatoprotective, Indian trumpet flower, Liver, liver health, natural cures, oroxylin-A, Oroxylum indicum, oxidative stress, scutellarin
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